Endocrine Abstracts

Objective: The most used therapeutic guidelines for the induction of male puberty in hypogonadotropic hypogonadism (HH) are GnRH in subcutaneous pulsatile infusion and HCG in monotherapy or combined with FSH in intramuscular injection. The objective of this study was to evaluate the efficacy of subcutaneous HCG with or without FSH in induction of male puberty in patients with HH.Patients and methods: Descriptive study of patients with HH treated with HCG...

Background: Acromegaly is the consequence of excessive growth hormone (GH) secretion, usually produced by a pituitary adenoma. Transphenoidal surgery is the first-choice treatment; however, the development of new drug therapies in the last years, specially the somatostatin analogues (SSA), has open new and promising avenues for the treatment of pituitary tumors.Objective: To determine whether a detailed knowledge of the clinico-pathological and radiologi...

Objective: To evaluate the efficacy of dapagliflozin for glycemic control and progression of weight loss after stabilization with liraglutide 1.8 mg.Patients and methods: Descriptive study: patients with tipo 2 diabetes (DM-2) in treatment with metformin and liraglutide 1.8 mg, optimal metabolic control, which after stabilization in weight loss, liraglutide is suspended and dapagliflozin is added. Variables analyzed baseline and at 6 months after treatme...

Objective: To evaluate the efficacy of canagliflozin 100 mg for glycemic control and progression of weight loss after stabilization with liraglutide 1.8 mg.Patients and methods: Descriptive study: patients with type 2 diabetes (DM-2) in treatment with metformin and liraglutide 1.8 mg, optimal metabolic control, which after stabilization in weight loss, liraglutide is suspended and canagliflozin 100 mg is added. Variables analyzed baseline and at 6 months...

Objetive: The change of treatment of liraglutide 1.8 mg to dapagliflozin or canaglifonzin 100 mg in patients with optimal glycemic control and stabilization weight loss, achieves progression in weight loss and improves the metabolic control of the patient with tipo 2 diabetes (DM-2). Our objective is to evaluate if there are differences in metabolic control and progression of weight loss in patients treated with canagliflozin 100 mg or dapagliflozin.Pati...

Objective: Preclinical studies have shown that DPP-4 inhibitors (iDPP4) have beneficial effects on functional mass of beta cells and pancreatic insulin content. The aim of this study is to evaluate the efficacy of treatment with sitagliptin in monotherapy or in combination with insulin in person with type 1 diabetes (DM-1) or type LADA diabetes (DM-LADA) of recent diagnosis.Patients and methods: Descriptive study: patients with DM-1 or DM-LADA in treatme...

Objectives: Pregnant women who are overweight or obese have an increased risk of complications during pregnancy, as do pregnant women with type 1 diabetes mellitus (DM1). The objective of this study is to describe the prevalence of overweight/obesity in pregnant women with DM1, and associated complications.Patients and methods: Retrospective descriptive study of pregnant women with DM1 (2004–2014). Variables analyzed: age, initial body mass index (B...

Objective: Obesity and overweight persist in patients with Cushing’s disease (CD) in remission, its persistence seems to be related to the duration of the disease. The aim of this study was to describe the persistence of overweight/obesity in patients with CD in remission and their relation to the duration of the disease.Patients and methods: Descriptive study of patients with CD (1995-2015). Variables analyzed: age, sex, body mass index (BMI), time...

Objective: Cardiovascular risk factors (CVRF) persist with notable prevalence in patients with Cushing’s disease (CD) after remission: obesity/overweight up to 40%, hypertension (HTA) up to 60%, type 2 diabetes (DM-2) up to 60% and dyslipidemia up to 30% of cases. Persistence of metabolic syndrome in patients with controlled CD seems to be related to the duration of the disease before remission. The aim of this study is to describe the prevalence of CVRF in patients with ...

Introduction: Flash glucose monitoring (FGM) allows non-invasive glucose level assessment. Studies have shown that patients using FGM test their glucose levels more often than those who use traditional blood glucose testing. Given that a higher rate of glucose testing has showed to improve glycemic control our objective was to describe the change in the glycemic control and time in euglycemic range in patients with FGM and the effect of the number of scans in this control....